therapeutic mouse anti ctla 4 Search Results


94
ATCC anti ctla4 monoclonal antibody
Anti Ctla4 Monoclonal Antibody, supplied by ATCC, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Novus Biologicals mouse anti ctla 4 antibodies
Mouse Anti Ctla 4 Antibodies, supplied by Novus Biologicals, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Becton Dickinson hamster anti-mouse ctla-4 (4f10
Hamster Anti Mouse Ctla 4 (4f10, supplied by Becton Dickinson, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Agenus Inc anti-ctla-4 antibody
Anti Ctla 4 Antibody, supplied by Agenus Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Cytek Biosciences ctla4
Ctla4, supplied by Cytek Biosciences, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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BioExpress mouse anti-ctla4 (uc10-4f10-11)
Mouse Anti Ctla4 (Uc10 4f10 11), supplied by BioExpress, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Thermo Fisher anti-mouse ctla-4 (cd152) pe
(A) The experimental scheme used for the suppression assays. (B) Analysis of CFSE-labeled WT T cell proliferation after 3 days of culture in the presence of Treg cells isolated from WT (blue) and KO (red) mice. The ratios indicate the relative numbers of CD4+CD25− Teff cells to CD4+CD25+ Treg cells plated on day 1. Histograms show the dilution of CFSE in Teff cells as measured by flow cytometry. The percentage of Teff cells showing dilution of the CFSE dye reflects the proportion of Teff cells that underwent cell division. Data are representative of four experiments. (C) Treg cells from the thymi and spleens of WT (blue) and KO (red) mice were identified by flow cytometry (Left: bivariant gating for CD4 and Foxp3) and further analyzed for the expression of the Treg cell functional markers CD39, CD73, and <t>CTLA4</t> (histograms). (D) Percentages of positive cells (left) and MFI values (right) for CD39, CD73, and CTLA4 in thymic and splenic CD4+Foxp3+ Tregs from WT and KO mice. The data were collected from two independent experiments with a total sample size of 4 mice. The P value was calculated by one-tailed unpaired t-test. (E) Cell surface expression of neuropilin-1 (Nrp-1) on thymic and splenic Treg cells (CD4+Foxp3+) from WT (blue) and KO (red) mice. (F) Bar graphs showing the percentage of positive cells (left) and MFI values (right) for Nrp-1 in thymic and splenic T cells from WT and KO mice. The data were collected from two independent experiments with a total sample size of four mice. The P value was calculated by one-tailed unpaired t-test.
Anti Mouse Ctla 4 (Cd152) Pe, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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94
fluidigm ctla 4
(A) The experimental scheme used for the suppression assays. (B) Analysis of CFSE-labeled WT T cell proliferation after 3 days of culture in the presence of Treg cells isolated from WT (blue) and KO (red) mice. The ratios indicate the relative numbers of CD4+CD25− Teff cells to CD4+CD25+ Treg cells plated on day 1. Histograms show the dilution of CFSE in Teff cells as measured by flow cytometry. The percentage of Teff cells showing dilution of the CFSE dye reflects the proportion of Teff cells that underwent cell division. Data are representative of four experiments. (C) Treg cells from the thymi and spleens of WT (blue) and KO (red) mice were identified by flow cytometry (Left: bivariant gating for CD4 and Foxp3) and further analyzed for the expression of the Treg cell functional markers CD39, CD73, and <t>CTLA4</t> (histograms). (D) Percentages of positive cells (left) and MFI values (right) for CD39, CD73, and CTLA4 in thymic and splenic CD4+Foxp3+ Tregs from WT and KO mice. The data were collected from two independent experiments with a total sample size of 4 mice. The P value was calculated by one-tailed unpaired t-test. (E) Cell surface expression of neuropilin-1 (Nrp-1) on thymic and splenic Treg cells (CD4+Foxp3+) from WT (blue) and KO (red) mice. (F) Bar graphs showing the percentage of positive cells (left) and MFI values (right) for Nrp-1 in thymic and splenic T cells from WT and KO mice. The data were collected from two independent experiments with a total sample size of four mice. The P value was calculated by one-tailed unpaired t-test.
Ctla 4, supplied by fluidigm, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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93
Proteintech anti cd68
(A) The experimental scheme used for the suppression assays. (B) Analysis of CFSE-labeled WT T cell proliferation after 3 days of culture in the presence of Treg cells isolated from WT (blue) and KO (red) mice. The ratios indicate the relative numbers of CD4+CD25− Teff cells to CD4+CD25+ Treg cells plated on day 1. Histograms show the dilution of CFSE in Teff cells as measured by flow cytometry. The percentage of Teff cells showing dilution of the CFSE dye reflects the proportion of Teff cells that underwent cell division. Data are representative of four experiments. (C) Treg cells from the thymi and spleens of WT (blue) and KO (red) mice were identified by flow cytometry (Left: bivariant gating for CD4 and Foxp3) and further analyzed for the expression of the Treg cell functional markers CD39, CD73, and <t>CTLA4</t> (histograms). (D) Percentages of positive cells (left) and MFI values (right) for CD39, CD73, and CTLA4 in thymic and splenic CD4+Foxp3+ Tregs from WT and KO mice. The data were collected from two independent experiments with a total sample size of 4 mice. The P value was calculated by one-tailed unpaired t-test. (E) Cell surface expression of neuropilin-1 (Nrp-1) on thymic and splenic Treg cells (CD4+Foxp3+) from WT (blue) and KO (red) mice. (F) Bar graphs showing the percentage of positive cells (left) and MFI values (right) for Nrp-1 in thymic and splenic T cells from WT and KO mice. The data were collected from two independent experiments with a total sample size of four mice. The P value was calculated by one-tailed unpaired t-test.
Anti Cd68, supplied by Proteintech, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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90
AstraZeneca ltd anti-mouse ctla4 migg1 clone 9d9
(A) The experimental scheme used for the suppression assays. (B) Analysis of CFSE-labeled WT T cell proliferation after 3 days of culture in the presence of Treg cells isolated from WT (blue) and KO (red) mice. The ratios indicate the relative numbers of CD4+CD25− Teff cells to CD4+CD25+ Treg cells plated on day 1. Histograms show the dilution of CFSE in Teff cells as measured by flow cytometry. The percentage of Teff cells showing dilution of the CFSE dye reflects the proportion of Teff cells that underwent cell division. Data are representative of four experiments. (C) Treg cells from the thymi and spleens of WT (blue) and KO (red) mice were identified by flow cytometry (Left: bivariant gating for CD4 and Foxp3) and further analyzed for the expression of the Treg cell functional markers CD39, CD73, and <t>CTLA4</t> (histograms). (D) Percentages of positive cells (left) and MFI values (right) for CD39, CD73, and CTLA4 in thymic and splenic CD4+Foxp3+ Tregs from WT and KO mice. The data were collected from two independent experiments with a total sample size of 4 mice. The P value was calculated by one-tailed unpaired t-test. (E) Cell surface expression of neuropilin-1 (Nrp-1) on thymic and splenic Treg cells (CD4+Foxp3+) from WT (blue) and KO (red) mice. (F) Bar graphs showing the percentage of positive cells (left) and MFI values (right) for Nrp-1 in thymic and splenic T cells from WT and KO mice. The data were collected from two independent experiments with a total sample size of four mice. The P value was calculated by one-tailed unpaired t-test.
Anti Mouse Ctla4 Migg1 Clone 9d9, supplied by AstraZeneca ltd, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Proteintech rabbit anti cd86
(A) The experimental scheme used for the suppression assays. (B) Analysis of CFSE-labeled WT T cell proliferation after 3 days of culture in the presence of Treg cells isolated from WT (blue) and KO (red) mice. The ratios indicate the relative numbers of CD4+CD25− Teff cells to CD4+CD25+ Treg cells plated on day 1. Histograms show the dilution of CFSE in Teff cells as measured by flow cytometry. The percentage of Teff cells showing dilution of the CFSE dye reflects the proportion of Teff cells that underwent cell division. Data are representative of four experiments. (C) Treg cells from the thymi and spleens of WT (blue) and KO (red) mice were identified by flow cytometry (Left: bivariant gating for CD4 and Foxp3) and further analyzed for the expression of the Treg cell functional markers CD39, CD73, and <t>CTLA4</t> (histograms). (D) Percentages of positive cells (left) and MFI values (right) for CD39, CD73, and CTLA4 in thymic and splenic CD4+Foxp3+ Tregs from WT and KO mice. The data were collected from two independent experiments with a total sample size of 4 mice. The P value was calculated by one-tailed unpaired t-test. (E) Cell surface expression of neuropilin-1 (Nrp-1) on thymic and splenic Treg cells (CD4+Foxp3+) from WT (blue) and KO (red) mice. (F) Bar graphs showing the percentage of positive cells (left) and MFI values (right) for Nrp-1 in thymic and splenic T cells from WT and KO mice. The data were collected from two independent experiments with a total sample size of four mice. The P value was calculated by one-tailed unpaired t-test.
Rabbit Anti Cd86, supplied by Proteintech, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Bio X Cell invivoplus anti mouse ctla 4 cd152 antibody

Invivoplus Anti Mouse Ctla 4 Cd152 Antibody, supplied by Bio X Cell, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Image Search Results


(A) The experimental scheme used for the suppression assays. (B) Analysis of CFSE-labeled WT T cell proliferation after 3 days of culture in the presence of Treg cells isolated from WT (blue) and KO (red) mice. The ratios indicate the relative numbers of CD4+CD25− Teff cells to CD4+CD25+ Treg cells plated on day 1. Histograms show the dilution of CFSE in Teff cells as measured by flow cytometry. The percentage of Teff cells showing dilution of the CFSE dye reflects the proportion of Teff cells that underwent cell division. Data are representative of four experiments. (C) Treg cells from the thymi and spleens of WT (blue) and KO (red) mice were identified by flow cytometry (Left: bivariant gating for CD4 and Foxp3) and further analyzed for the expression of the Treg cell functional markers CD39, CD73, and CTLA4 (histograms). (D) Percentages of positive cells (left) and MFI values (right) for CD39, CD73, and CTLA4 in thymic and splenic CD4+Foxp3+ Tregs from WT and KO mice. The data were collected from two independent experiments with a total sample size of 4 mice. The P value was calculated by one-tailed unpaired t-test. (E) Cell surface expression of neuropilin-1 (Nrp-1) on thymic and splenic Treg cells (CD4+Foxp3+) from WT (blue) and KO (red) mice. (F) Bar graphs showing the percentage of positive cells (left) and MFI values (right) for Nrp-1 in thymic and splenic T cells from WT and KO mice. The data were collected from two independent experiments with a total sample size of four mice. The P value was calculated by one-tailed unpaired t-test.

Journal: Science signaling

Article Title: Targeting the ion channel TRPM7 promotes the thymic development of regulatory T cells by promoting IL-2 signaling

doi: 10.1126/scisignal.abb0619

Figure Lengend Snippet: (A) The experimental scheme used for the suppression assays. (B) Analysis of CFSE-labeled WT T cell proliferation after 3 days of culture in the presence of Treg cells isolated from WT (blue) and KO (red) mice. The ratios indicate the relative numbers of CD4+CD25− Teff cells to CD4+CD25+ Treg cells plated on day 1. Histograms show the dilution of CFSE in Teff cells as measured by flow cytometry. The percentage of Teff cells showing dilution of the CFSE dye reflects the proportion of Teff cells that underwent cell division. Data are representative of four experiments. (C) Treg cells from the thymi and spleens of WT (blue) and KO (red) mice were identified by flow cytometry (Left: bivariant gating for CD4 and Foxp3) and further analyzed for the expression of the Treg cell functional markers CD39, CD73, and CTLA4 (histograms). (D) Percentages of positive cells (left) and MFI values (right) for CD39, CD73, and CTLA4 in thymic and splenic CD4+Foxp3+ Tregs from WT and KO mice. The data were collected from two independent experiments with a total sample size of 4 mice. The P value was calculated by one-tailed unpaired t-test. (E) Cell surface expression of neuropilin-1 (Nrp-1) on thymic and splenic Treg cells (CD4+Foxp3+) from WT (blue) and KO (red) mice. (F) Bar graphs showing the percentage of positive cells (left) and MFI values (right) for Nrp-1 in thymic and splenic T cells from WT and KO mice. The data were collected from two independent experiments with a total sample size of four mice. The P value was calculated by one-tailed unpaired t-test.

Article Snippet: The following antibodies were used: anti-mouse neuropilin-1-PE (R&D Systems, #FAB5994P), rat anti-mouse CD25 PE-Cy7 (BD Pharmingen, #552880), anti-mouse CD39 PE-Cyanine7 (eBioscience, Inc. #25-0391), anti-mouse CD73 PE (eBioscience, Inc. #12-0731), rat anti-mouse CD4 FITC (BD Biosciences #553046), purified hamster anti-mouse CD28 (BD Biosciences #553294), anti-mouse/rat Foxp3 APC clone FJK-16s (eBioscience), anti-Foxp3 (eBioscience, #17-5773), purified hamster anti-mouse CD3ε chain, clone 145-2C11 (BD Biosciences #553058), anti-mouse CTLA-4 (CD152) PE (eBioscience, #12-1522), and anti-mouse CD16/CD32 antibody (Biolegend,TruStain fcX, #101320).

Techniques: Labeling, Isolation, Flow Cytometry, Expressing, Functional Assay, One-tailed Test

Journal: Cell Reports Medicine

Article Title: Effector T cell responses unleashed by regulatory T cell ablation exacerbate oral squamous cell carcinoma

doi: 10.1016/j.xcrm.2021.100399

Figure Lengend Snippet:

Article Snippet: InVivoPlus anti-mouse CTLA-4 (CD152) antibody, clone 9D9 , BioXCell , Cat# BE0164, RRID: AB_10949609.

Techniques: Recombinant, Infection, Transfection, Cell Isolation, Selection, Staining, Sequencing, Transgenic Assay, Expressing, Software